| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xcel_0390 | Xcel_0391 | Xcel_0390 | Xcel_0391 | PFAM: major intrinsic protein; KEGG: azc:AZC_2711 glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | PFAM: FAD dependent oxidoreductase; KEGG: vei:Veis_2018 FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.945 |
| Xcel_0390 | glpK | Xcel_0390 | Xcel_0389 | PFAM: major intrinsic protein; KEGG: azc:AZC_2711 glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.944 |
| Xcel_0391 | Xcel_0390 | Xcel_0391 | Xcel_0390 | PFAM: FAD dependent oxidoreductase; KEGG: vei:Veis_2018 FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | PFAM: major intrinsic protein; KEGG: azc:AZC_2711 glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.945 |
| Xcel_0391 | Xcel_0878 | Xcel_0391 | Xcel_0878 | PFAM: FAD dependent oxidoreductase; KEGG: vei:Veis_2018 FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | PFAM: major intrinsic protein; KEGG: bmv:BMASAVP1_A2707 glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.778 |
| Xcel_0391 | glpK | Xcel_0391 | Xcel_0389 | PFAM: FAD dependent oxidoreductase; KEGG: vei:Veis_2018 FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.999 |
| Xcel_0459 | arc | Xcel_0459 | Xcel_1485 | 2-alkenal reductase; KEGG: afw:Anae109_2046 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein. | AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.902 |
| Xcel_0459 | glpK | Xcel_0459 | Xcel_0389 | 2-alkenal reductase; KEGG: afw:Anae109_2046 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.789 |
| Xcel_0459 | prcA | Xcel_0459 | Xcel_1489 | 2-alkenal reductase; KEGG: afw:Anae109_2046 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein. | 20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.467 |
| Xcel_0459 | prcB | Xcel_0459 | Xcel_1488 | 2-alkenal reductase; KEGG: afw:Anae109_2046 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein. | 20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.467 |
| Xcel_0878 | Xcel_0391 | Xcel_0878 | Xcel_0391 | PFAM: major intrinsic protein; KEGG: bmv:BMASAVP1_A2707 glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | PFAM: FAD dependent oxidoreductase; KEGG: vei:Veis_2018 FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.778 |
| Xcel_0878 | glpK | Xcel_0878 | Xcel_0389 | PFAM: major intrinsic protein; KEGG: bmv:BMASAVP1_A2707 glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.852 |
| Xcel_1313 | arc | Xcel_1313 | Xcel_1485 | PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: afw:Anae109_0073 2-alkenal reductase. | AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.902 |
| Xcel_1313 | glpK | Xcel_1313 | Xcel_0389 | PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: afw:Anae109_0073 2-alkenal reductase. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.789 |
| Xcel_1313 | prcA | Xcel_1313 | Xcel_1489 | PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: afw:Anae109_0073 2-alkenal reductase. | 20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.467 |
| Xcel_1313 | prcB | Xcel_1313 | Xcel_1488 | PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: afw:Anae109_0073 2-alkenal reductase. | 20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.467 |
| Xcel_1338 | glpK | Xcel_1338 | Xcel_0389 | TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bat:BAS4827 phosphatase. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.913 |
| Xcel_3203 | glpK | Xcel_3203 | Xcel_0389 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: vpa:VP0793 glucose-specific PTS system component. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.837 |
| arc | Xcel_0459 | Xcel_1485 | Xcel_0459 | AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 2-alkenal reductase; KEGG: afw:Anae109_2046 protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein. | 0.902 |
| arc | Xcel_1313 | Xcel_1485 | Xcel_1313 | AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: afw:Anae109_0073 2-alkenal reductase. | 0.902 |
| arc | glpK | Xcel_1485 | Xcel_0389 | AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.980 |