| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xcel_0002 | Xcel_0285 | Xcel_0002 | Xcel_0285 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Non-specific serine/threonine protein kinase; KEGG: mxa:MXAN_5351 SNF2/helicase domain protein; PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. | 0.747 |
| Xcel_0002 | Xcel_0723 | Xcel_0002 | Xcel_0723 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: bsu:BSU06610 ATP-dependent DNA helicase. | 0.801 |
| Xcel_0002 | Xcel_0779 | Xcel_0002 | Xcel_0779 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: UvrD/REP helicase; KEGG: mpo:Mpop_4135 UvrD/REP helicase. | 0.772 |
| Xcel_0002 | Xcel_0786 | Xcel_0002 | Xcel_0786 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; KEGG: gsu:GSU3411 ATP-dependent DNA helicase PcrA, putative. | 0.973 |
| Xcel_0002 | Xcel_2129 | Xcel_0002 | Xcel_2129 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, epsilon subunit; KEGG: eba:ebA3500 nuclease subunit Cho of the excinuclease complex (UvrC homolog protein); TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease. | 0.983 |
| Xcel_0002 | Xcel_3280 | Xcel_0002 | Xcel_3280 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: 5'-3' exonuclease; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; KEGG: pca:Pcar_2864 DNA polymerase I. | 0.956 |
| Xcel_0002 | polA | Xcel_0002 | Xcel_1509 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.997 |
| Xcel_0002 | recA | Xcel_0002 | Xcel_1242 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.914 |
| Xcel_0002 | topA | Xcel_0002 | Xcel_0344 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.822 |
| Xcel_0285 | Xcel_0002 | Xcel_0285 | Xcel_0002 | Non-specific serine/threonine protein kinase; KEGG: mxa:MXAN_5351 SNF2/helicase domain protein; PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.747 |
| Xcel_0285 | Xcel_0779 | Xcel_0285 | Xcel_0779 | Non-specific serine/threonine protein kinase; KEGG: mxa:MXAN_5351 SNF2/helicase domain protein; PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. | PFAM: UvrD/REP helicase; KEGG: mpo:Mpop_4135 UvrD/REP helicase. | 0.571 |
| Xcel_0285 | Xcel_0786 | Xcel_0285 | Xcel_0786 | Non-specific serine/threonine protein kinase; KEGG: mxa:MXAN_5351 SNF2/helicase domain protein; PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. | PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; KEGG: gsu:GSU3411 ATP-dependent DNA helicase PcrA, putative. | 0.907 |
| Xcel_0285 | Xcel_3280 | Xcel_0285 | Xcel_3280 | Non-specific serine/threonine protein kinase; KEGG: mxa:MXAN_5351 SNF2/helicase domain protein; PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. | PFAM: 5'-3' exonuclease; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; KEGG: pca:Pcar_2864 DNA polymerase I. | 0.604 |
| Xcel_0285 | polA | Xcel_0285 | Xcel_1509 | Non-specific serine/threonine protein kinase; KEGG: mxa:MXAN_5351 SNF2/helicase domain protein; PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.821 |
| Xcel_0285 | recA | Xcel_0285 | Xcel_1242 | Non-specific serine/threonine protein kinase; KEGG: mxa:MXAN_5351 SNF2/helicase domain protein; PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.701 |
| Xcel_0285 | topA | Xcel_0285 | Xcel_0344 | Non-specific serine/threonine protein kinase; KEGG: mxa:MXAN_5351 SNF2/helicase domain protein; PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.488 |
| Xcel_0723 | Xcel_0002 | Xcel_0723 | Xcel_0002 | TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: bsu:BSU06610 ATP-dependent DNA helicase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.801 |
| Xcel_0723 | Xcel_0779 | Xcel_0723 | Xcel_0779 | TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: bsu:BSU06610 ATP-dependent DNA helicase. | PFAM: UvrD/REP helicase; KEGG: mpo:Mpop_4135 UvrD/REP helicase. | 0.412 |
| Xcel_0723 | Xcel_0780 | Xcel_0723 | Xcel_0780 | TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: bsu:BSU06610 ATP-dependent DNA helicase. | PFAM: UvrD/REP helicase; KEGG: acr:Acry_0218 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | 0.928 |
| Xcel_0723 | Xcel_0786 | Xcel_0723 | Xcel_0786 | TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: bsu:BSU06610 ATP-dependent DNA helicase. | PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; KEGG: gsu:GSU3411 ATP-dependent DNA helicase PcrA, putative. | 0.969 |