node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Xcel_0756 | Xcel_0902 | Xcel_0756 | Xcel_0902 | PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: aba:Acid345_1451 3-demethylubiquinone-9 3- methyltransferase. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | 0.554 |
Xcel_0902 | Xcel_0756 | Xcel_0902 | Xcel_0756 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: aba:Acid345_1451 3-demethylubiquinone-9 3- methyltransferase. | 0.554 |
Xcel_0902 | Xcel_0903 | Xcel_0902 | Xcel_0903 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | PFAM: Domain of unknown function DUF1918. | 0.543 |
Xcel_0902 | Xcel_1797 | Xcel_0902 | Xcel_1797 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | 0.677 |
Xcel_0902 | Xcel_1876 | Xcel_0902 | Xcel_1876 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | 0.730 |
Xcel_0902 | thyA | Xcel_0902 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
Xcel_0903 | Xcel_0902 | Xcel_0903 | Xcel_0902 | PFAM: Domain of unknown function DUF1918. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | 0.543 |
Xcel_1797 | Xcel_0902 | Xcel_1797 | Xcel_0902 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | 0.677 |
Xcel_1797 | thyA | Xcel_1797 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
Xcel_1876 | Xcel_0902 | Xcel_1876 | Xcel_0902 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | 0.730 |
Xcel_1876 | thyA | Xcel_1876 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
thyA | Xcel_0902 | Xcel_2834 | Xcel_0902 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | 0.604 |
thyA | Xcel_1797 | Xcel_2834 | Xcel_1797 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | 0.604 |
thyA | Xcel_1876 | Xcel_2834 | Xcel_1876 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | 0.604 |