| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xcel_0270 | Xcel_2543 | Xcel_0270 | Xcel_2543 | Fructokinase; PFAM: PfkB domain protein; KEGG: sme:SMc02164 fructokinase protein; Belongs to the carbohydrate kinase PfkB family. | TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: scl:sce4699 mannose-6-phosphate isomerase. | 0.912 |
| Xcel_0270 | glmS | Xcel_0270 | Xcel_0667 | Fructokinase; PFAM: PfkB domain protein; KEGG: sme:SMc02164 fructokinase protein; Belongs to the carbohydrate kinase PfkB family. | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.910 |
| Xcel_0270 | nagB | Xcel_0270 | Xcel_1049 | Fructokinase; PFAM: PfkB domain protein; KEGG: sme:SMc02164 fructokinase protein; Belongs to the carbohydrate kinase PfkB family. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. | 0.909 |
| Xcel_0270 | pgi | Xcel_0270 | Xcel_0183 | Fructokinase; PFAM: PfkB domain protein; KEGG: sme:SMc02164 fructokinase protein; Belongs to the carbohydrate kinase PfkB family. | PFAM: phosphoglucose isomerase (PGI); KEGG: acp:A2cp1_3272 glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.917 |
| Xcel_1046 | Xcel_1047 | Xcel_1046 | Xcel_1047 | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0710 ABC transporter, permease. | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: lch:Lcho_3327 binding-protein-dependent transport systems inner membrane component. | 0.994 |
| Xcel_1046 | Xcel_1048 | Xcel_1046 | Xcel_1048 | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0710 ABC transporter, permease. | PFAM: ROK family protein; KEGG: glo:Glov_1263 ROK family protein. | 0.819 |
| Xcel_1046 | nagB | Xcel_1046 | Xcel_1049 | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0710 ABC transporter, permease. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. | 0.820 |
| Xcel_1047 | Xcel_1046 | Xcel_1047 | Xcel_1046 | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: lch:Lcho_3327 binding-protein-dependent transport systems inner membrane component. | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0710 ABC transporter, permease. | 0.994 |
| Xcel_1047 | Xcel_1048 | Xcel_1047 | Xcel_1048 | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: lch:Lcho_3327 binding-protein-dependent transport systems inner membrane component. | PFAM: ROK family protein; KEGG: glo:Glov_1263 ROK family protein. | 0.798 |
| Xcel_1047 | nagB | Xcel_1047 | Xcel_1049 | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: lch:Lcho_3327 binding-protein-dependent transport systems inner membrane component. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. | 0.798 |
| Xcel_1048 | Xcel_1046 | Xcel_1048 | Xcel_1046 | PFAM: ROK family protein; KEGG: glo:Glov_1263 ROK family protein. | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0710 ABC transporter, permease. | 0.819 |
| Xcel_1048 | Xcel_1047 | Xcel_1048 | Xcel_1047 | PFAM: ROK family protein; KEGG: glo:Glov_1263 ROK family protein. | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: lch:Lcho_3327 binding-protein-dependent transport systems inner membrane component. | 0.798 |
| Xcel_1048 | nagB | Xcel_1048 | Xcel_1049 | PFAM: ROK family protein; KEGG: glo:Glov_1263 ROK family protein. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. | 0.822 |
| Xcel_1048 | pgi | Xcel_1048 | Xcel_0183 | PFAM: ROK family protein; KEGG: glo:Glov_1263 ROK family protein. | PFAM: phosphoglucose isomerase (PGI); KEGG: acp:A2cp1_3272 glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.931 |
| Xcel_2123 | Xcel_2442 | Xcel_2123 | Xcel_2442 | N-acylglucosamine-6-phosphate 2-epimerase; PFAM: putative N-acetylmannosamine-6-phosphate epimerase; deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: esa:ESA_00529 N-acetylmannosamine-6-phosphate 2-epimerase. | N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: gdi:GDI2579 putative N-acetylglucosamine-6- phosphate deacetylase. | 0.954 |
| Xcel_2123 | nagB | Xcel_2123 | Xcel_1049 | N-acylglucosamine-6-phosphate 2-epimerase; PFAM: putative N-acetylmannosamine-6-phosphate epimerase; deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: esa:ESA_00529 N-acetylmannosamine-6-phosphate 2-epimerase. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. | 0.829 |
| Xcel_2442 | Xcel_2123 | Xcel_2442 | Xcel_2123 | N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: gdi:GDI2579 putative N-acetylglucosamine-6- phosphate deacetylase. | N-acylglucosamine-6-phosphate 2-epimerase; PFAM: putative N-acetylmannosamine-6-phosphate epimerase; deoxyribose-phosphate aldolase/phospho-2- dehydro-3-deoxyheptonate aldolase; KEGG: esa:ESA_00529 N-acetylmannosamine-6-phosphate 2-epimerase. | 0.954 |
| Xcel_2442 | glmM | Xcel_2442 | Xcel_0663 | N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: gdi:GDI2579 putative N-acetylglucosamine-6- phosphate deacetylase. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.954 |
| Xcel_2442 | glmS | Xcel_2442 | Xcel_0667 | N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: gdi:GDI2579 putative N-acetylglucosamine-6- phosphate deacetylase. | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.956 |
| Xcel_2442 | nagB | Xcel_2442 | Xcel_1049 | N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: gdi:GDI2579 putative N-acetylglucosamine-6- phosphate deacetylase. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. | 0.999 |