STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xcel_1096KEGG: sml:Smlt0110 putative viral-like DNA topoisomerase. (326 aa)    
Predicted Functional Partners:
Xcel_0786
PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; KEGG: gsu:GSU3411 ATP-dependent DNA helicase PcrA, putative.
    
 
 0.879
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.839
Xcel_1988
DNA topoisomerase (ATP-hydrolyzing); KEGG: bha:BH0006 DNA gyrase subunit B; PFAM: DNA gyrase subunit B domain protein; TOPRIM domain protein; ATP-binding region ATPase domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein.
   
 
 0.839
Xcel_1173
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
 
 0.739
Xcel_1402
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: psa:PST_2128 oxidoreductase, short chain dehydrogenase/reductase family.
  
 
   0.705
Xcel_2090
KEGG: bpt:Bpet0900 DNA helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP- dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; HRDC domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein.
   
 
 0.692
Xcel_1305
KEGG: maq:Maqu_0559 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase.
    
 
 0.691
Xcel_1097
PFAM: acyl-CoA thioesterase; KEGG: ret:RHE_CH03975 acyl-CoA thioesterase II protein.
       0.645
Xcel_1098
PFAM: globin; KEGG: bha:BH2854 hypothetical protein.
       0.645
Xcel_2233
TIGRFAM: DNA polymerase LigD, polymerase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; DNA primase small subunit; ATP dependent DNA ligase domain protein; KEGG: mpt:Mpe_B0011 ATP-dependent DNA ligase.
 
 
 
 0.640
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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