STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (320 aa)    
Predicted Functional Partners:
Xcel_1505
KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 0.977
Xcel_2132
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.938
Xcel_1895
KEGG: rru:Rru_A3000 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C- acetyltransferase glycine radical.
   
 
 0.932
Xcel_2098
PFAM: Transketolase central region; Transketolase domain protein; KEGG: afw:Anae109_1994 transketolase central region.
   
 0.921
Xcel_3222
PFAM: Transketolase central region; Transketolase domain protein; KEGG: ank:AnaeK_2034 transketolase domain protein.
   
 0.921
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: acp:A2cp1_3272 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.917
Xcel_1699
Lactate 2-monooxygenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: oxidoreductase.
   
 
 0.913
Xcel_2432
Pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; KEGG: scl:sce4570 phosphoenolpyruvate synthase.
  
 
 0.912
Xcel_3206
KEGG: gdi:GDI1318 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; PEP- utilizing protein; Belongs to the PEP-utilizing enzyme family.
  
 
 0.912
Xcel_2097
PFAM: dehydrogenase E1 component; KEGG: gsu:GSU2654 pyruvate dehydrogenase complex E1 component, alpha subunit.
   
 
 0.911
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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