STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (343 aa)    
Predicted Functional Partners:
Xcel_1342
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
 0.962
nadE
NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.961
Xcel_1340
Hemolysin A; KEGG: mex:Mext_4311 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein.
  
  
 0.960
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.946
Xcel_2246
TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: hap:HAPS_2213 NAD(P) transhydrogenase subunit alpha.
     
 0.919
Xcel_2245
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.907
Xcel_0784
PFAM: NUDIX hydrolase; Zinc ribbon NADH pyrophosphatase; NADH pyrophosphatase-like; KEGG: sfu:Sfum_1412 NUDIX hydrolase.
     
 0.902
Xcel_1337
KEGG: dvl:Dvul_2077 hypothetical protein.
 
   
 0.834
Xcel_1343
PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: bha:BH2771 hypothetical protein.
       0.819
Xcel_1339
Hypothetical protein.
       0.773
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.