STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xcel_1484tRNA methyltransferase complex GCD14 subunit; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (334 aa)    
Predicted Functional Partners:
Xcel_1481
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rpa:RPA4337 HAD-superfamily hydrolase subfamily IA, variant 3.
      0.924
Xcel_1483
PFAM: peptidase M50; KEGG: mxa:MXAN_1115 SREBP protease/CBS domain; Belongs to the peptidase M50B family.
      0.852
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
 
     0.766
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
 
 0.744
Xcel_1486
PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; KEGG: rpc:RPC_1449 hypothetical protein.
 
    0.731
rpmD
TIGRFAM: ribosomal protein L30; PFAM: ribosomal protein L30; KEGG: bha:BH0152 50S ribosomal protein L30.
   
   0.715
pafA
Protein of unknown function DUF245 domain protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
 
    0.677
Xcel_1914
PFAM: deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase; KEGG: sus:Acid_5841 23S rRNA (uracil-5-)- methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
   
  
 0.625
Xcel_3299
TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumB; PFAM: (Uracil-5)-methyltransferase; KEGG: ypm:YP_1257 23S rRNA methyluridine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
   
  
 0.625
prcB
20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
 
 
   0.589
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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