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prcA protein (Xylanimonas cellulosilytica) - STRING interaction network
"prcA" - Proteasome subunit alpha in Xylanimonas cellulosilytica
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
prcAProteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation; Belongs to the peptidase T1A family (244 aa)    
Predicted Functional Partners:
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation; Belongs to the peptidase T1B family (270 aa)
 
  0.999
pafA
Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (457 aa)
     
  0.989
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a ’key in a lock’ to induce gate opening and therefore regulate proteolysis (543 aa)
 
 
  0.973
pup
Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (68 aa)
 
     
  0.899
Xcel_0169
Uncharacterized protein; KEGG- Hdgfl1; hepatoma derived growth factor-like 1 (209 aa)
   
 
 
  0.892
Xcel_1486
PFAM- protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; KEGG- rpc-RPC_1449 hypothetical protein (545 aa)
     
  0.852
Xcel_1491
Peptidyl-prolyl cis-trans isomerase; PFAM- peptidylprolyl isomerase FKBP-type; KEGG- mxa-MXAN_4085 peptidylprolyl cis-trans isomerase, FKBP-type (305 aa)
   
      0.715
Xcel_1493
PFAM- ABC transporter related; ABC transporter transmembrane region; SMART- AAA ATPase; KEGG- oan-Oant_3334 ABC transporter related (605 aa)
 
      0.700
Xcel_1494
PFAM- ABC transporter related; ABC transporter transmembrane region; SMART- AAA ATPase; KEGG- rsh-Rsph17029_3808 ABC transporter related (595 aa)
   
      0.654
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (256 aa)
              0.611
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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