STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Xcel_1626TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. (531 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.985
Xcel_0718
Sulfite reductase (ferredoxin); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: aba:Acid345_2373 nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like.
 
  
 0.969
Xcel_1813
PFAM: Uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; KEGG: scl:sce6449 putative transcriptional regulator.
 
 
 0.960
Xcel_3253
Uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 
 0.954
Xcel_0711
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rce:RC1_2177 siroheme synthase.
 
 
0.953
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.945
Xcel_1625
TIGRFAM: nitrite reductase [NAD(P)H], small subunit; KEGG: pcr:Pcryo_1318 nitrite reductase (NAD(P)H) large subunit, NirD.
  
  
 0.940
Xcel_3254
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: scl:sce0016 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.931
Xcel_0717
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.928
Xcel_1624
TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta- component ferrodoxin domain protein; KEGG: rme:Rmet_4818 assimilatory nitrite reductase (NAD(P)H) large subunit precursor.
 
  
 0.869
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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