STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xcel_1699Lactate 2-monooxygenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: oxidoreductase. (434 aa)    
Predicted Functional Partners:
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.920
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.920
Xcel_0913
PFAM: Aldehyde Dehydrogenase; KEGG: mxa:MXAN_5040 aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
 
 
 0.917
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.913
Xcel_3016
PFAM: FAD linked oxidase domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: noc:Noc_0464 hypothetical protein.
  
 
 0.679
Xcel_0307
PFAM: NADH:flavin oxidoreductase/NADH oxidase; monooxygenase FAD-binding; KEGG: scl:sce8661 oxidoreductase.
  
  
 0.650
Xcel_1700
PFAM: major facilitator superfamily MFS_1; KEGG: maq:Maqu_2937 major facilitator superfamily transporter.
       0.623
Xcel_2617
PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 0.566
der
Cytidylate kinase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the cytidylate kinase family. Type 1 subfamily.
  
  
 0.563
Xcel_1697
PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: pla:Plav_2904 glycerophosphoryl diester phosphodiesterase.
       0.561
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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