| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xcel_0741 | Xcel_1720 | Xcel_0741 | Xcel_1720 | PFAM: major intrinsic protein; KEGG: sil:SPO0970 aquaporin Z; Belongs to the MIP/aquaporin (TC 1.A.8) family. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | 0.428 |
| Xcel_0936 | Xcel_1720 | Xcel_0936 | Xcel_1720 | PFAM: carbonic anhydrase; KEGG: mno:Mnod_1487 carbonic anhydrase. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | 0.620 |
| Xcel_0936 | Xcel_3096 | Xcel_0936 | Xcel_3096 | PFAM: carbonic anhydrase; KEGG: mno:Mnod_1487 carbonic anhydrase. | KEGG: pde:Pden_3937 transferase hexapeptide protein. | 0.924 |
| Xcel_1720 | Xcel_0741 | Xcel_1720 | Xcel_0741 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | PFAM: major intrinsic protein; KEGG: sil:SPO0970 aquaporin Z; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.428 |
| Xcel_1720 | Xcel_0936 | Xcel_1720 | Xcel_0936 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | PFAM: carbonic anhydrase; KEGG: mno:Mnod_1487 carbonic anhydrase. | 0.620 |
| Xcel_1720 | Xcel_3096 | Xcel_1720 | Xcel_3096 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | KEGG: pde:Pden_3937 transferase hexapeptide protein. | 0.696 |
| Xcel_1720 | metK | Xcel_1720 | Xcel_1718 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.523 |
| Xcel_1720 | priA | Xcel_1720 | Xcel_1719 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.802 |
| Xcel_1720 | rpoZ | Xcel_1720 | Xcel_1716 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.403 |
| Xcel_3096 | Xcel_0936 | Xcel_3096 | Xcel_0936 | KEGG: pde:Pden_3937 transferase hexapeptide protein. | PFAM: carbonic anhydrase; KEGG: mno:Mnod_1487 carbonic anhydrase. | 0.924 |
| Xcel_3096 | Xcel_1720 | Xcel_3096 | Xcel_1720 | KEGG: pde:Pden_3937 transferase hexapeptide protein. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | 0.696 |
| metK | Xcel_1720 | Xcel_1718 | Xcel_1720 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | 0.523 |
| metK | priA | Xcel_1718 | Xcel_1719 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.567 |
| metK | rpoZ | Xcel_1718 | Xcel_1716 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.618 |
| priA | Xcel_1720 | Xcel_1719 | Xcel_1720 | Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | 0.802 |
| priA | metK | Xcel_1719 | Xcel_1718 | Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.567 |
| priA | rpoZ | Xcel_1719 | Xcel_1716 | Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.655 |
| rpoZ | Xcel_1720 | Xcel_1716 | Xcel_1720 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bcm:Bcenmc03_0488 HAD family hydrolase. | 0.403 |
| rpoZ | metK | Xcel_1716 | Xcel_1718 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.618 |
| rpoZ | priA | Xcel_1716 | Xcel_1719 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | Primosomal protein N' (replication factor Y) - superfamily II helicase-like protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.655 |