| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xcel_0181 | Xcel_1754 | Xcel_0181 | Xcel_1754 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: oan:Oant_1327 bifunctional deaminase- reductase domain protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | 0.765 |
| Xcel_0181 | Xcel_1797 | Xcel_0181 | Xcel_1797 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: oan:Oant_1327 bifunctional deaminase- reductase domain protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | 0.692 |
| Xcel_0181 | thyA | Xcel_0181 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: oan:Oant_1327 bifunctional deaminase- reductase domain protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
| Xcel_0288 | Xcel_1797 | Xcel_0288 | Xcel_1797 | PFAM: NAD-dependent epimerase/dehydratase; KEGG: gbe:GbCGDNIH1_1597 quinate/shikimate dehydrogenase. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | 0.443 |
| Xcel_0902 | Xcel_1797 | Xcel_0902 | Xcel_1797 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | 0.677 |
| Xcel_0902 | thyA | Xcel_0902 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
| Xcel_1400 | Xcel_1754 | Xcel_1400 | Xcel_1754 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ank:AnaeK_4011 bifunctional deaminase- reductase domain protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | 0.745 |
| Xcel_1400 | Xcel_1797 | Xcel_1400 | Xcel_1797 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ank:AnaeK_4011 bifunctional deaminase- reductase domain protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | 0.554 |
| Xcel_1400 | thyA | Xcel_1400 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ank:AnaeK_4011 bifunctional deaminase- reductase domain protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
| Xcel_1754 | Xcel_0181 | Xcel_1754 | Xcel_0181 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: oan:Oant_1327 bifunctional deaminase- reductase domain protein. | 0.765 |
| Xcel_1754 | Xcel_1400 | Xcel_1754 | Xcel_1400 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ank:AnaeK_4011 bifunctional deaminase- reductase domain protein. | 0.745 |
| Xcel_1754 | Xcel_1797 | Xcel_1754 | Xcel_1797 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | 0.711 |
| Xcel_1754 | thyA | Xcel_1754 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
| Xcel_1794 | Xcel_1795 | Xcel_1794 | Xcel_1795 | PFAM: UTP--glucose-1-phosphate uridylyltransferase; KEGG: UGP/PGM; UDP-Glucose- Pyrophosphorylase/Phosphoglucomutase. | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: cti:RALTA_A1178 hypothetical protein; Belongs to the SUA5 family. | 0.618 |
| Xcel_1794 | Xcel_1796 | Xcel_1794 | Xcel_1796 | PFAM: UTP--glucose-1-phosphate uridylyltransferase; KEGG: UGP/PGM; UDP-Glucose- Pyrophosphorylase/Phosphoglucomutase. | Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pol:Bpro_4368 transcriptional regulator, LysR family. | 0.456 |
| Xcel_1794 | Xcel_1797 | Xcel_1794 | Xcel_1797 | PFAM: UTP--glucose-1-phosphate uridylyltransferase; KEGG: UGP/PGM; UDP-Glucose- Pyrophosphorylase/Phosphoglucomutase. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | 0.408 |
| Xcel_1795 | Xcel_1794 | Xcel_1795 | Xcel_1794 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: cti:RALTA_A1178 hypothetical protein; Belongs to the SUA5 family. | PFAM: UTP--glucose-1-phosphate uridylyltransferase; KEGG: UGP/PGM; UDP-Glucose- Pyrophosphorylase/Phosphoglucomutase. | 0.618 |
| Xcel_1795 | Xcel_1796 | Xcel_1795 | Xcel_1796 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: cti:RALTA_A1178 hypothetical protein; Belongs to the SUA5 family. | Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pol:Bpro_4368 transcriptional regulator, LysR family. | 0.560 |
| Xcel_1795 | Xcel_1797 | Xcel_1795 | Xcel_1797 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: cti:RALTA_A1178 hypothetical protein; Belongs to the SUA5 family. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. | 0.505 |
| Xcel_1796 | Xcel_1794 | Xcel_1796 | Xcel_1794 | Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pol:Bpro_4368 transcriptional regulator, LysR family. | PFAM: UTP--glucose-1-phosphate uridylyltransferase; KEGG: UGP/PGM; UDP-Glucose- Pyrophosphorylase/Phosphoglucomutase. | 0.456 |