node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Xcel_0711 | Xcel_1626 | Xcel_0711 | Xcel_1626 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rce:RC1_2177 siroheme synthase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | 0.953 |
Xcel_0711 | Xcel_1812 | Xcel_0711 | Xcel_1812 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rce:RC1_2177 siroheme synthase. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rso:RS03744 putative transmembrane protein. | 0.911 |
Xcel_0711 | Xcel_1813 | Xcel_0711 | Xcel_1813 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rce:RC1_2177 siroheme synthase. | PFAM: Uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; KEGG: scl:sce6449 putative transcriptional regulator. | 0.935 |
Xcel_0711 | Xcel_3253 | Xcel_0711 | Xcel_3253 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rce:RC1_2177 siroheme synthase. | Uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.933 |
Xcel_0711 | Xcel_3254 | Xcel_0711 | Xcel_3254 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rce:RC1_2177 siroheme synthase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: scl:sce0016 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.885 |
Xcel_0711 | hemC | Xcel_0711 | Xcel_3252 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rce:RC1_2177 siroheme synthase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.990 |
Xcel_0711 | hemE | Xcel_0711 | Xcel_3249 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rce:RC1_2177 siroheme synthase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.918 |
Xcel_1626 | Xcel_0711 | Xcel_1626 | Xcel_0711 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rce:RC1_2177 siroheme synthase. | 0.953 |
Xcel_1626 | Xcel_1812 | Xcel_1626 | Xcel_1812 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rso:RS03744 putative transmembrane protein. | 0.580 |
Xcel_1626 | Xcel_1813 | Xcel_1626 | Xcel_1813 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | PFAM: Uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; KEGG: scl:sce6449 putative transcriptional regulator. | 0.960 |
Xcel_1626 | Xcel_1814 | Xcel_1626 | Xcel_1814 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | TIGRFAM: nitrite reductase [NAD(P)H], small subunit; KEGG: mfa:Mfla_0318 nitrite reductase (NAD(P)H) large subunit, NirD. | 0.745 |
Xcel_1626 | Xcel_1815 | Xcel_1626 | Xcel_1815 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta- component ferrodoxin domain protein; KEGG: reu:Reut_B4860 assimilatory nitrite reductase (NAD(P)H) large subunit precursor. | 0.448 |
Xcel_1626 | Xcel_3253 | Xcel_1626 | Xcel_3253 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | Uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.954 |
Xcel_1626 | Xcel_3254 | Xcel_1626 | Xcel_3254 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: scl:sce0016 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.931 |
Xcel_1626 | hemC | Xcel_1626 | Xcel_3252 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.985 |
Xcel_1626 | hemE | Xcel_1626 | Xcel_3249 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.945 |
Xcel_1812 | Xcel_0711 | Xcel_1812 | Xcel_0711 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rso:RS03744 putative transmembrane protein. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rce:RC1_2177 siroheme synthase. | 0.911 |
Xcel_1812 | Xcel_1626 | Xcel_1812 | Xcel_1626 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rso:RS03744 putative transmembrane protein. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rce:RC1_2177 siroheme synthase. | 0.580 |
Xcel_1812 | Xcel_1813 | Xcel_1812 | Xcel_1813 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rso:RS03744 putative transmembrane protein. | PFAM: Uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; KEGG: scl:sce6449 putative transcriptional regulator. | 0.953 |
Xcel_1812 | Xcel_1814 | Xcel_1812 | Xcel_1814 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: rso:RS03744 putative transmembrane protein. | TIGRFAM: nitrite reductase [NAD(P)H], small subunit; KEGG: mfa:Mfla_0318 nitrite reductase (NAD(P)H) large subunit, NirD. | 0.792 |