| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xcel_0181 | Xcel_1754 | Xcel_0181 | Xcel_1754 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: oan:Oant_1327 bifunctional deaminase- reductase domain protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | 0.765 |
| Xcel_0181 | Xcel_1876 | Xcel_0181 | Xcel_1876 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: oan:Oant_1327 bifunctional deaminase- reductase domain protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | 0.717 |
| Xcel_0181 | thyA | Xcel_0181 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: oan:Oant_1327 bifunctional deaminase- reductase domain protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
| Xcel_0902 | Xcel_1876 | Xcel_0902 | Xcel_1876 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | 0.730 |
| Xcel_0902 | thyA | Xcel_0902 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
| Xcel_1400 | Xcel_1754 | Xcel_1400 | Xcel_1754 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ank:AnaeK_4011 bifunctional deaminase- reductase domain protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | 0.745 |
| Xcel_1400 | Xcel_1876 | Xcel_1400 | Xcel_1876 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ank:AnaeK_4011 bifunctional deaminase- reductase domain protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | 0.680 |
| Xcel_1400 | thyA | Xcel_1400 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ank:AnaeK_4011 bifunctional deaminase- reductase domain protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
| Xcel_1754 | Xcel_0181 | Xcel_1754 | Xcel_0181 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: oan:Oant_1327 bifunctional deaminase- reductase domain protein. | 0.765 |
| Xcel_1754 | Xcel_1400 | Xcel_1754 | Xcel_1400 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ank:AnaeK_4011 bifunctional deaminase- reductase domain protein. | 0.745 |
| Xcel_1754 | Xcel_1876 | Xcel_1754 | Xcel_1876 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | 0.596 |
| Xcel_1754 | thyA | Xcel_1754 | Xcel_2834 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.604 |
| Xcel_1866 | Xcel_1876 | Xcel_1866 | Xcel_1876 | PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: cti:RALTA_B1837 conserved hypothetical protein, DUF704. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | 0.424 |
| Xcel_1874 | Xcel_1875 | Xcel_1874 | Xcel_1875 | Hypothetical protein. | PFAM: aminotransferase class IV; KEGG: azc:AZC_1597 4-amino-4-deoxychorismate lyase. | 0.447 |
| Xcel_1874 | Xcel_1876 | Xcel_1874 | Xcel_1876 | Hypothetical protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | 0.447 |
| Xcel_1874 | Xcel_1877 | Xcel_1874 | Xcel_1877 | Hypothetical protein. | PFAM: Chorismate binding-like; KEGG: met:M446_0053 para-aminobenzoate synthase, subunit I. | 0.447 |
| Xcel_1875 | Xcel_1874 | Xcel_1875 | Xcel_1874 | PFAM: aminotransferase class IV; KEGG: azc:AZC_1597 4-amino-4-deoxychorismate lyase. | Hypothetical protein. | 0.447 |
| Xcel_1875 | Xcel_1876 | Xcel_1875 | Xcel_1876 | PFAM: aminotransferase class IV; KEGG: azc:AZC_1597 4-amino-4-deoxychorismate lyase. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | 0.776 |
| Xcel_1875 | Xcel_1877 | Xcel_1875 | Xcel_1877 | PFAM: aminotransferase class IV; KEGG: azc:AZC_1597 4-amino-4-deoxychorismate lyase. | PFAM: Chorismate binding-like; KEGG: met:M446_0053 para-aminobenzoate synthase, subunit I. | 0.922 |
| Xcel_1876 | Xcel_0181 | Xcel_1876 | Xcel_0181 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_6866 deaminase-reductase domain- containing protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: oan:Oant_1327 bifunctional deaminase- reductase domain protein. | 0.717 |