| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xcel_0616 | Xcel_1884 | Xcel_0616 | Xcel_1884 | KEGG: hypothetical protein. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: msl:Msil_2108 riboflavin biosynthesis protein RibD. | 0.442 |
| Xcel_0978 | Xcel_1149 | Xcel_0978 | Xcel_1149 | KEGG: ank:AnaeK_2371 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gme:Gmet_2475 folylpolyglutamate synthetase. | 0.996 |
| Xcel_0978 | Xcel_1884 | Xcel_0978 | Xcel_1884 | KEGG: ank:AnaeK_2371 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: msl:Msil_2108 riboflavin biosynthesis protein RibD. | 0.533 |
| Xcel_0978 | Xcel_2984 | Xcel_0978 | Xcel_2984 | KEGG: ank:AnaeK_2371 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| Xcel_0978 | ribA | Xcel_0978 | Xcel_1728 | KEGG: ank:AnaeK_2371 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.446 |
| Xcel_0978 | ribH | Xcel_0978 | Xcel_1729 | KEGG: ank:AnaeK_2371 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.521 |
| Xcel_1149 | Xcel_0978 | Xcel_1149 | Xcel_0978 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gme:Gmet_2475 folylpolyglutamate synthetase. | KEGG: ank:AnaeK_2371 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | 0.996 |
| Xcel_1149 | Xcel_1215 | Xcel_1149 | Xcel_1215 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gme:Gmet_2475 folylpolyglutamate synthetase. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: glo:Glov_1649 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.461 |
| Xcel_1149 | Xcel_1884 | Xcel_1149 | Xcel_1884 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gme:Gmet_2475 folylpolyglutamate synthetase. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: msl:Msil_2108 riboflavin biosynthesis protein RibD. | 0.590 |
| Xcel_1149 | Xcel_2984 | Xcel_1149 | Xcel_2984 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gme:Gmet_2475 folylpolyglutamate synthetase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.932 |
| Xcel_1149 | ribA | Xcel_1149 | Xcel_1728 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gme:Gmet_2475 folylpolyglutamate synthetase. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.533 |
| Xcel_1215 | Xcel_1149 | Xcel_1215 | Xcel_1149 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: glo:Glov_1649 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gme:Gmet_2475 folylpolyglutamate synthetase. | 0.461 |
| Xcel_1215 | Xcel_1727 | Xcel_1215 | Xcel_1727 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: glo:Glov_1649 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: glo:Glov_1750 riboflavin synthase, alpha subunit. | 0.928 |
| Xcel_1215 | Xcel_1884 | Xcel_1215 | Xcel_1884 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: glo:Glov_1649 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: msl:Msil_2108 riboflavin biosynthesis protein RibD. | 0.733 |
| Xcel_1215 | Xcel_2984 | Xcel_1215 | Xcel_2984 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: glo:Glov_1649 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.583 |
| Xcel_1215 | ribA | Xcel_1215 | Xcel_1728 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: glo:Glov_1649 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.808 |
| Xcel_1215 | ribH | Xcel_1215 | Xcel_1729 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: glo:Glov_1649 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.955 |
| Xcel_1727 | Xcel_1215 | Xcel_1727 | Xcel_1215 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: glo:Glov_1750 riboflavin synthase, alpha subunit. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: glo:Glov_1649 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.928 |
| Xcel_1727 | Xcel_1884 | Xcel_1727 | Xcel_1884 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: glo:Glov_1750 riboflavin synthase, alpha subunit. | PFAM: bifunctional deaminase-reductase domain protein; KEGG: msl:Msil_2108 riboflavin biosynthesis protein RibD. | 0.746 |
| Xcel_1727 | Xcel_2984 | Xcel_1727 | Xcel_2984 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: glo:Glov_1750 riboflavin synthase, alpha subunit. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.490 |