STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xcel_2046Glutamate-ammonia ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (1037 aa)    
Predicted Functional Partners:
Xcel_2047
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sat:SYN_01628 glutamine synthetase.
  
  
 0.913
Xcel_2038
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: afw:Anae109_4400 glutamine synthetase, type I.
 
  
 0.907
Xcel_1164
UTP-GlnB uridylyltransferase, GlnD; PFAM: GlnD PII-uridylyltransferase; metal-dependent phosphohydrolase HD sub domain; DNA polymerase beta domain protein region; protein of unknown function DUF294 nucleotidyltransferase putative; KEGG: ade:Adeh_1692 metal dependent phosphohydrolase.
 
   
 0.797
Xcel_1891
PFAM: 3'-5' exonuclease; HRDC domain protein; SMART: 3'-5' exonuclease; HRDC domain protein; KEGG: dol:Dole_3191 3'-5' exonuclease.
  
     0.728
Xcel_1163
PFAM: nitrogen regulatory protein P-II; KEGG: dal:Dalk_5099 nitrogen regulatory protein P- II; Belongs to the P(II) protein family.
 
 
 
 0.711
Xcel_1924
Hypothetical protein.
  
     0.690
Xcel_1741
SMART: regulatory protein MerR; KEGG: afw:Anae109_4225 MerR family transcriptional regulator.
  
     0.678
crgA
Protein of unknown function UPF0233; Involved in cell division; Belongs to the CrgA family.
  
   
 0.659
Xcel_1503
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin).
     
 0.628
rbpA-2
Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
     0.625
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.