STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xcel_2101PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: rce:RC1_0381 methylcrotonoyl-CoA carboxylase subunit alpha. (792 aa)    
Predicted Functional Partners:
Xcel_1021
PFAM: carboxyl transferase; KEGG: sus:Acid_1492 carboxyl transferase.
 
 0.999
Xcel_2100
Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: cak:Caul_3154 propionyl-CoA carboxylase.
 0.999
Xcel_2107
KEGG: cvi:CV_2790 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.983
Xcel_2099
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: ade:Adeh_1825 pyruvate dehydrogenase-like complex E2 component.
  
 0.980
Xcel_2135
(Acyl-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase; KEGG: sml:Smlt1028 putative malonyl CoA-acyl carrier protein transacylase.
 
 
 0.980
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.972
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.953
Xcel_2381
KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.953
Xcel_0082
KEGG: hypothetical protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1.
 
  
 0.933
Xcel_1892
KEGG: sfu:Sfum_1403 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.930
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.