STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kuKu protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (274 aa)    
Predicted Functional Partners:
Xcel_2233
TIGRFAM: DNA polymerase LigD, polymerase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; DNA primase small subunit; ATP dependent DNA ligase domain protein; KEGG: mpt:Mpe_B0011 ATP-dependent DNA ligase.
 
  
 0.983
Xcel_1674
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: afw:Anae109_4038 ATP-dependent DNA ligase.
 
  
 0.941
Xcel_1675
TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit; KEGG: afw:Anae109_2830 DNA primase small subunit.
 
  
 0.893
Xcel_2642
KEGG: acp:A2cp1_4312 DNA ligase I, ATP-dependent Dnl1; TIGRFAM: DNA ligase I, ATP-dependent Dnl1; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA ligase domain protein; Belongs to the ATP-dependent DNA ligase family.
 
  
 0.878
Xcel_1096
KEGG: sml:Smlt0110 putative viral-like DNA topoisomerase.
 
    0.619
Xcel_2230
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mes:Meso_2206 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
       0.618
Xcel_2231
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; KEGG: ppf:Pput_2591 XRE family transcriptional regulator.
       0.467
Xcel_2232
PFAM: RelA/SpoT domain protein; KEGG: bha:BH1885 hypothetical protein.
       0.450
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
      
 0.420
Xcel_0723
TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: bsu:BSU06610 ATP-dependent DNA helicase.
      
 0.418
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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