STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (218 aa)    
Predicted Functional Partners:
nadE
NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
 
 0.983
Xcel_1052
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 0.972
Xcel_0348
KEGG: ccs:CCNA_03009 nicotinate-nucleotide pyrophosphorylase (carboxylating); TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
    
 0.964
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
  
 0.962
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
 
 0.946
Xcel_1237
PFAM: CinA domain protein; KEGG: dvm:DvMF_0903 CinA domain protein; Belongs to the CinA family.
  
 
 0.935
Xcel_2246
TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: hap:HAPS_2213 NAD(P) transhydrogenase subunit alpha.
     
 0.909
Xcel_0784
PFAM: NUDIX hydrolase; Zinc ribbon NADH pyrophosphatase; NADH pyrophosphatase-like; KEGG: sfu:Sfum_1412 NUDIX hydrolase.
     
 0.906
Xcel_2245
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.902
Xcel_3091
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; nucleic acid binding OB-fold tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; Carbohydrate-binding family V/XII; SMART: Carbohydrate-binding family V/XII; KEGG: rpb:RPB_0803 5'-nucleotidase.
   
 
  0.901
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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