STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xcel_2279ATP-dependent DNA helicase RecG; KEGG: mrd:Mrad2831_1662 DEAD/DEAH box helicase domain-containing protein; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: DEAD-like helicase; helicase domain protein. (749 aa)    
Predicted Functional Partners:
Xcel_2280
PFAM: Dak phosphatase; KEGG: bca:BCE_3898 phosphatase, putative.
 
    0.921
Xcel_2855
Putative transcriptional regulator; PFAM: AAA-4 family protein; KEGG: tbd:Tbd_2681 transcriptional regulator.
     
  0.900
Xcel_2888
Putative transcriptional regulator; PFAM: AAA-4 family protein; KEGG: csa:Csal_0085 putative transcriptional regulator.
     
  0.900
Xcel_3059
Putative transcriptional regulator; PFAM: AAA-4 family protein; KEGG: noc:Noc_0057 hypothetical protein.
     
  0.900
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
   
 0.747
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.667
Xcel_2278
TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; KEGG: met:M446_6054 methyltransferase.
       0.651
rpmB
TIGRFAM: ribosomal protein L28; PFAM: ribosomal protein L28; KEGG: aba:Acid345_0165 LSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family.
     
 0.636
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.616
Xcel_2272
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
     
 0.609
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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