STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xcel_2289Transcriptional regulator, AraC family; PFAM: ThiJ/PfpI domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pol:Bpro_4080 transcriptional regulator, AraC family with amidase-like domain. (332 aa)    
Predicted Functional Partners:
Xcel_2290
PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: rsq:Rsph17025_4330 hypothetical protein.
       0.705
Xcel_1762
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: cti:RALTA_B0884 putative transcriptional regulator, AraC family, isolated domain.
 
 
 0.636
Xcel_2288
PFAM: major facilitator superfamily MFS_1; KEGG: bid:Bind_1234 major facilitator transporter.
 
     0.634
Xcel_1435
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: mmr:Mmar10_2206 AraC family transcriptional regulator.
 
 
 0.520
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.509
Xcel_3318
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bbr:BB1236 putative glyxalase.
 
    0.474
Xcel_2291
KEGG: scl:sce7916 hypothetical protein.
       0.452
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
   0.418
Xcel_0033
PFAM: NmrA family protein; KEGG: nar:Saro_2808 NmrA-like.
 
    0.402
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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