STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xcel_2379PFAM: biotin/lipoate A/B protein ligase; KEGG: ilo:IL0300 lipoate-protein ligase A. (358 aa)    
Predicted Functional Partners:
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.968
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 
 0.942
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
   
 0.929
Xcel_2487
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; KEGG: sus:Acid_5307 alpha-ketoglutarate decarboxylase.
  
 0.929
Xcel_2030
KEGG: aba:Acid345_4350 2-oxoglutarate dehydrogenase E2 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein.
 
 0.797
Xcel_3221
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: bba:Bd0779 pyruvate dehydrogenase E2.
 
 0.791
Xcel_2099
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: ade:Adeh_1825 pyruvate dehydrogenase-like complex E2 component.
 
 0.787
Xcel_1007
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: pla:Plav_3138 dihydrolipoamide dehydrogenase.
 
 
 0.780
Xcel_1076
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: mxa:MXAN_0278 mercuric reductase, truncated.
 
 
 0.768
Xcel_2352
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; HI0933 family protein; KEGG: mlo:mlr0388 dihydrolipoamide dehydrogenase.
 
 
 0.749
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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