| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xcel_1023 | Xcel_1505 | Xcel_1023 | Xcel_1505 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.909 |
| Xcel_1023 | Xcel_1673 | Xcel_1023 | Xcel_1673 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.902 |
| Xcel_1023 | Xcel_2232 | Xcel_1023 | Xcel_2232 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | PFAM: RelA/SpoT domain protein; KEGG: bha:BH1885 hypothetical protein. | 0.900 |
| Xcel_1023 | Xcel_2300 | Xcel_1023 | Xcel_2300 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | KEGG: pmu:PM0940 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | 0.900 |
| Xcel_1023 | Xcel_2481 | Xcel_1023 | Xcel_2481 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | KEGG: abo:ABO_0867 hypothetical protein. | 0.900 |
| Xcel_1023 | folE | Xcel_1023 | Xcel_2986 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | KEGG: bha:BH1646 GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I. | 0.800 |
| Xcel_1023 | moaA | Xcel_1023 | Xcel_1832 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.814 |
| Xcel_1023 | ndk | Xcel_1023 | Xcel_1158 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.912 |
| Xcel_1023 | ribA | Xcel_1023 | Xcel_1728 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.807 |
| Xcel_1505 | Xcel_1023 | Xcel_1505 | Xcel_1023 | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | 0.909 |
| Xcel_1505 | Xcel_1673 | Xcel_1505 | Xcel_1673 | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.909 |
| Xcel_1505 | Xcel_2232 | Xcel_1505 | Xcel_2232 | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | PFAM: RelA/SpoT domain protein; KEGG: bha:BH1885 hypothetical protein. | 0.900 |
| Xcel_1505 | Xcel_2300 | Xcel_1505 | Xcel_2300 | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | KEGG: pmu:PM0940 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | 0.900 |
| Xcel_1505 | Xcel_2481 | Xcel_1505 | Xcel_2481 | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | KEGG: abo:ABO_0867 hypothetical protein. | 0.900 |
| Xcel_1505 | folE | Xcel_1505 | Xcel_2986 | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | KEGG: bha:BH1646 GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I. | 0.812 |
| Xcel_1505 | moaA | Xcel_1505 | Xcel_1832 | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.800 |
| Xcel_1505 | ndk | Xcel_1505 | Xcel_1158 | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.911 |
| Xcel_1505 | ribA | Xcel_1505 | Xcel_1728 | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.800 |
| Xcel_1673 | Xcel_1023 | Xcel_1673 | Xcel_1023 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:RL0458 putative adenylate cyclase. | 0.902 |
| Xcel_1673 | Xcel_1505 | Xcel_1673 | Xcel_1505 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | KEGG: ade:Adeh_4234 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.909 |