| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xcel_0568 | ahcY | Xcel_0568 | Xcel_2526 | PFAM: C-5 cytosine-specific DNA methylase; KEGG: hch:HCH_02855 site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.909 |
| Xcel_0696 | Xcel_1111 | Xcel_0696 | Xcel_1111 | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: acr:Acry_2560 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.920 |
| Xcel_0696 | Xcel_1840 | Xcel_0696 | Xcel_1840 | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.902 |
| Xcel_0696 | Xcel_1940 | Xcel_0696 | Xcel_1940 | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.927 |
| Xcel_0696 | Xcel_2290 | Xcel_0696 | Xcel_2290 | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: rsq:Rsph17025_4330 hypothetical protein. | 0.944 |
| Xcel_0696 | Xcel_2638 | Xcel_0696 | Xcel_2638 | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | 0.952 |
| Xcel_0696 | Xcel_2671 | Xcel_0696 | Xcel_2671 | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | Cystathionine beta-synthase; KEGG: acp:A2cp1_3846 pyridoxal-5'-phosphate- dependent protein beta subunit; TIGRFAM: cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein. | 0.920 |
| Xcel_0696 | Xcel_3001 | Xcel_0696 | Xcel_3001 | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: bha:BH2603 O-acetylhomoserine aminocarboxypropyltransferase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein. | 0.932 |
| Xcel_0696 | ahcY | Xcel_0696 | Xcel_2526 | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.900 |
| Xcel_0696 | metZ | Xcel_0696 | Xcel_3120 | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.942 |
| Xcel_1111 | Xcel_0696 | Xcel_1111 | Xcel_0696 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: acr:Acry_2560 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | 0.920 |
| Xcel_1111 | Xcel_1840 | Xcel_1111 | Xcel_1840 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: acr:Acry_2560 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.858 |
| Xcel_1111 | Xcel_1940 | Xcel_1111 | Xcel_1940 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: acr:Acry_2560 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.891 |
| Xcel_1111 | Xcel_2290 | Xcel_1111 | Xcel_2290 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: acr:Acry_2560 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: rsq:Rsph17025_4330 hypothetical protein. | 0.974 |
| Xcel_1111 | Xcel_2638 | Xcel_1111 | Xcel_2638 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: acr:Acry_2560 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | 0.975 |
| Xcel_1111 | Xcel_2671 | Xcel_1111 | Xcel_2671 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: acr:Acry_2560 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cystathionine beta-synthase; KEGG: acp:A2cp1_3846 pyridoxal-5'-phosphate- dependent protein beta subunit; TIGRFAM: cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein. | 0.816 |
| Xcel_1111 | Xcel_3001 | Xcel_1111 | Xcel_3001 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: acr:Acry_2560 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: bha:BH2603 O-acetylhomoserine aminocarboxypropyltransferase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein. | 0.840 |
| Xcel_1111 | ahcY | Xcel_1111 | Xcel_2526 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: acr:Acry_2560 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.861 |
| Xcel_1111 | metZ | Xcel_1111 | Xcel_3120 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: acr:Acry_2560 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.973 |
| Xcel_1840 | Xcel_0696 | Xcel_1840 | Xcel_0696 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | PFAM: aminotransferase class I and II; KEGG: mes:Meso_2643 aminotransferase, class I and II. | 0.902 |