| node1 | node2 | node1 annotation | node2 annotation | score |
| Xcel_1291 | Xcel_2618 | PFAM: DivIVA family protein; KEGG: bha:BH2546 cell-division initiation protein (septum placement). | PFAM: aldo/keto reductase; KEGG: mrd:Mrad2831_5462 aldo/keto reductase. | 0.447 |
| Xcel_1940 | Xcel_2405 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: apa:APP7_1068 alcohol dehydrogenase / acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.519 |
| Xcel_1940 | Xcel_2617 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.522 |
| Xcel_1940 | Xcel_2618 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: aldo/keto reductase; KEGG: mrd:Mrad2831_5462 aldo/keto reductase. | 0.681 |
| Xcel_2405 | Xcel_1940 | PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: apa:APP7_1068 alcohol dehydrogenase / acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.519 |
| Xcel_2405 | Xcel_2617 | PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: apa:APP7_1068 alcohol dehydrogenase / acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.838 |
| Xcel_2405 | Xcel_2618 | PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: apa:APP7_1068 alcohol dehydrogenase / acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | PFAM: aldo/keto reductase; KEGG: mrd:Mrad2831_5462 aldo/keto reductase. | 0.468 |
| Xcel_2405 | Xcel_2621 | PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: apa:APP7_1068 alcohol dehydrogenase / acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: ppd:Ppro_1713 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.415 |
| Xcel_2405 | Xcel_2949 | PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: apa:APP7_1068 alcohol dehydrogenase / acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | TIGRFAM: trehalose-phosphatase; PFAM: glycosyl transferase family 20; trehalose- phosphatase; KEGG: scl:sce0488 Alpha,alpha-trehalose-phosphate synthase (UDP-forming). | 0.444 |
| Xcel_2617 | Xcel_1940 | PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.522 |
| Xcel_2617 | Xcel_2405 | PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: apa:APP7_1068 alcohol dehydrogenase / acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.838 |
| Xcel_2617 | Xcel_2618 | PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | PFAM: aldo/keto reductase; KEGG: mrd:Mrad2831_5462 aldo/keto reductase. | 0.691 |
| Xcel_2617 | Xcel_2619 | PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system. | 0.471 |
| Xcel_2617 | Xcel_2620 | PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | PFAM: PilT protein domain protein; KEGG: mca:MCA1623 virulence associated protein VagD, putative. | 0.542 |
| Xcel_2617 | Xcel_2621 | PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: ppd:Ppro_1713 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.970 |
| Xcel_2617 | Xcel_2622 | PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: acp:A2cp1_0395 modification methylase, HemK family. | 0.400 |
| Xcel_2617 | Xcel_2949 | PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: dal:Dalk_3943 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | TIGRFAM: trehalose-phosphatase; PFAM: glycosyl transferase family 20; trehalose- phosphatase; KEGG: scl:sce0488 Alpha,alpha-trehalose-phosphate synthase (UDP-forming). | 0.459 |
| Xcel_2618 | Xcel_1291 | PFAM: aldo/keto reductase; KEGG: mrd:Mrad2831_5462 aldo/keto reductase. | PFAM: DivIVA family protein; KEGG: bha:BH2546 cell-division initiation protein (septum placement). | 0.447 |
| Xcel_2618 | Xcel_1940 | PFAM: aldo/keto reductase; KEGG: mrd:Mrad2831_5462 aldo/keto reductase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.681 |
| Xcel_2618 | Xcel_2405 | PFAM: aldo/keto reductase; KEGG: mrd:Mrad2831_5462 aldo/keto reductase. | PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: apa:APP7_1068 alcohol dehydrogenase / acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.468 |