STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (381 aa)    
Predicted Functional Partners:
Xcel_3250
PFAM: FAD dependent oxidoreductase; KEGG: csa:Csal_0796 protoporphyrinogen oxidase.
 
 
 0.996
Xcel_2623
PFAM: Chlorite dismutase; KEGG: bha:BH3825 putative heme peroxidase.
  
 0.995
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.972
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.922
Xcel_2758
PFAM: Haem oxygenase-like; KEGG: HMOX2; heme oxygenase (decycling) 2; K00510 heme oxygenase.
    
 0.922
Xcel_3125
PFAM: Radical SAM domain protein; KEGG: sus:Acid_7329 radical SAM domain-containing protein.
  
 
 0.920
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.831
Xcel_1925
PFAM: inositol monophosphatase; KEGG: mxa:MXAN_1914 inositol-1-monophosphatase.
      0.612
Xcel_3254
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: scl:sce0016 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.589
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.583
Your Current Organism:
Xylanimonas cellulosilytica
NCBI taxonomy Id: 446471
Other names: X. cellulosilytica DSM 15894, Xylanimonas cellulosilytica DSM 15894, Xylanimonas cellulosilytica str. DSM 15894, Xylanimonas cellulosilytica strain DSM 15894
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