agnE protein (Dictyostelium discoideum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

agnE

Argonaut-like protein. (1200 aa)

Predicted Functional Partners:

drnB

0.816

DrnA

0.759

rrpA

0.758

rrpC

0.756

cbfA

0.712

Dhx9

0.668

Snd1

0.619

helF

0.581

DDB_G0271884

0.527

Dhx57

0.512

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB_G0271884	agnE	Q869N7	Q54HL3	PKS_ER domain-containing protein.	Argonaut-like protein.	0.527
DDB_G0271884	rrpA	Q869N7	Q54H25	PKS_ER domain-containing protein.	RNA-directed RNA polymerase.	0.405
DDB_G0271884	rrpC	Q869N7	Q54UI6	PKS_ER domain-containing protein.	RNA-directed RNA polymerase.	0.404
Dhx57	Snd1	Q55GT9	Q54WH0	Uncharacterized protein.	Uncharacterized protein.	0.496
Dhx57	agnE	Q55GT9	Q54HL3	Uncharacterized protein.	Argonaut-like protein.	0.512
Dhx9	DrnA	Q869Z1	Q95ZG5	Uncharacterized protein.	Putative RNase III.	0.654
Dhx9	Snd1	Q869Z1	Q54WH0	Uncharacterized protein.	Uncharacterized protein.	0.496
Dhx9	agnE	Q869Z1	Q54HL3	Uncharacterized protein.	Argonaut-like protein.	0.668
Dhx9	drnB	Q869Z1	Q55FS1	Uncharacterized protein.	Uncharacterized protein.	0.533
Dhx9	helF	Q869Z1	Q86L44	Uncharacterized protein.	Uncharacterized protein.	0.820
DrnA	Dhx9	Q95ZG5	Q869Z1	Putative RNase III.	Uncharacterized protein.	0.654
DrnA	agnE	Q95ZG5	Q54HL3	Putative RNase III.	Argonaut-like protein.	0.759
DrnA	cbfA	Q95ZG5	O97101	Putative RNase III.	C-module-binding factor A; Transcriptional regulator involved in phagocytosis and pinocytosis. Both activates and represses transcription. Regulates expression of acaA, carA, pkaC, csaA, cotB and lagC. Promotes amplification of the tRNA gene-associated retrotransposon TRE5-A, a mobile genetic element formerly called as Dictyostelium repetitive element (DRE). Suppresses agnC and agnE encoding argonaute proteins which are part of a RNA interference pathway controlling TRE5-A amplification. Required for amplification of both sense and antisense RNA transcripts, but does not activate their [...]	0.408
DrnA	helF	Q95ZG5	Q86L44	Putative RNase III.	Uncharacterized protein.	0.811
DrnA	rrpA	Q95ZG5	Q54H25	Putative RNase III.	RNA-directed RNA polymerase.	0.808
DrnA	rrpC	Q95ZG5	Q54UI6	Putative RNase III.	RNA-directed RNA polymerase.	0.808
Snd1	Dhx57	Q54WH0	Q55GT9	Uncharacterized protein.	Uncharacterized protein.	0.496
Snd1	Dhx9	Q54WH0	Q869Z1	Uncharacterized protein.	Uncharacterized protein.	0.496
Snd1	agnE	Q54WH0	Q54HL3	Uncharacterized protein.	Argonaut-like protein.	0.619
Snd1	drnB	Q54WH0	Q55FS1	Uncharacterized protein.	Uncharacterized protein.	0.599