STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alfAAlpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (461 aa)    
Predicted Functional Partners:
DDB0202938
Fucosidase_C domain-containing protein; Belongs to the glycosyl hydrolase 29 family.
  
  
 
0.901
DDB0168638
Uncharacterized protein.
      
 0.818
pXi
Probable serine/threonine-protein kinase pXi; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
      
 0.784
alyL
Putative lysozyme-like protein; Belongs to the dictyostelium lysozyme family.
      
 0.701
glb1
Beta-galactosidase 1; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
 
  
 0.469
copb
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
      
 0.450
alyA
Lysozyme A; Has antibacterial activity against the Gram-positive bacteria B.subtilis, B.megaterium and M.luteus. No antibacterial activity detected against the Gram-positive bacterium S.aureus or against the Gram-negative bacterium E.coli. Lacks chitinase activity.
      
 0.450
DDB0217722
Ig_mannosidase domain-containing protein.
     
 0.446
mhsp70
Heat shock 70 kDa protein, mitochondrial; May function in protein folding and assembly, and disassembly of protein complexes; Belongs to the heat shock protein 70 family.
      
 0.437
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.