node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AY055590 | pkgC | Q95UC5 | P34102 | Dipeptidyl aminopeptidase. | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.744 |
atp5f1d | pkgC | Q55F42 | P34102 | ATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.576 |
dnapkcs | piaA | Q54UC0 | O77203 | DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Is recruited to DNA ends by the Ku70/Ku80 heterodimer and is involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (By similarity). This activity is only apparent when DNA damage is administered in G1 phase of the cell cycle. Required for efficient signaling of DNA double-stranded breaks via phosphorylation of H2AX during G1; Belongs to the PI3/PI4-kinase family. DNAPK subfamily. | Protein pianissimo A; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein- mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function re [...] | 0.857 |
dnapkcs | pkgC | Q54UC0 | P34102 | DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Is recruited to DNA ends by the Ku70/Ku80 heterodimer and is involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (By similarity). This activity is only apparent when DNA damage is administered in G1 phase of the cell cycle. Required for efficient signaling of DNA double-stranded breaks via phosphorylation of H2AX during G1; Belongs to the PI3/PI4-kinase family. DNAPK subfamily. | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.547 |
dnapkcs | raptor | Q54UC0 | Q55BR7 | DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Is recruited to DNA ends by the Ku70/Ku80 heterodimer and is involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (By similarity). This activity is only apparent when DNA damage is administered in G1 phase of the cell cycle. Required for efficient signaling of DNA double-stranded breaks via phosphorylation of H2AX during G1; Belongs to the PI3/PI4-kinase family. DNAPK subfamily. | Protein raptor homolog. | 0.864 |
pdkA | pkgC | Q54TW2 | P34102 | Probable serine/threonine-protein kinase pdkA. | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.590 |
pdkB | pkgC | Q54PK9 | P34102 | 3-phosphoinositide-dependent protein kinase B. | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.603 |
piaA | dnapkcs | O77203 | Q54UC0 | Protein pianissimo A; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein- mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function re [...] | DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Is recruited to DNA ends by the Ku70/Ku80 heterodimer and is involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (By similarity). This activity is only apparent when DNA damage is administered in G1 phase of the cell cycle. Required for efficient signaling of DNA double-stranded breaks via phosphorylation of H2AX during G1; Belongs to the PI3/PI4-kinase family. DNAPK subfamily. | 0.857 |
piaA | pkgC | O77203 | P34102 | Protein pianissimo A; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein- mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function re [...] | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.597 |
piaA | raptor | O77203 | Q55BR7 | Protein pianissimo A; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein- mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function re [...] | Protein raptor homolog. | 0.934 |
piaA | smg1 | O77203 | Q553E9 | Protein pianissimo A; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein- mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function re [...] | Probable serine/threonine-protein kinase smg1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating upf1 (By similarity). | 0.857 |
piaA | tor | O77203 | Q86C65 | Protein pianissimo A; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein- mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function re [...] | Serine/threonine-protein kinase tor; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Functions as a part of 2 distinct protein complexes TORC1 and TORC2. TORC1 is a rapamycin-sensitive complex that controls cell growth in response to nutrients and growth factors. The second TOR complex, TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2 but not TORC1 negatively regulates phagocytosis. TORC2-dependent regulation of the cytoskeleton may follow differential phosphorylation of pkbA. May have some protein [...] | 0.970 |
pkaR | pkgC | P05987 | P34102 | cAMP-dependent protein kinase regulatory subunit. | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.563 |
pkgC | AY055590 | P34102 | Q95UC5 | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | Dipeptidyl aminopeptidase. | 0.744 |
pkgC | atp5f1d | P34102 | Q55F42 | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | ATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] | 0.576 |
pkgC | dnapkcs | P34102 | Q54UC0 | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Is recruited to DNA ends by the Ku70/Ku80 heterodimer and is involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (By similarity). This activity is only apparent when DNA damage is administered in G1 phase of the cell cycle. Required for efficient signaling of DNA double-stranded breaks via phosphorylation of H2AX during G1; Belongs to the PI3/PI4-kinase family. DNAPK subfamily. | 0.547 |
pkgC | pdkA | P34102 | Q54TW2 | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | Probable serine/threonine-protein kinase pdkA. | 0.590 |
pkgC | pdkB | P34102 | Q54PK9 | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 3-phosphoinositide-dependent protein kinase B. | 0.603 |
pkgC | piaA | P34102 | O77203 | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | Protein pianissimo A; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein- mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function re [...] | 0.597 |
pkgC | pkaR | P34102 | P05987 | Protein kinase 3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | cAMP-dependent protein kinase regulatory subunit. | 0.563 |