STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvpAMajor vault protein alpha; Unknown, though MVP-alpha is required for normal vault structure. (843 aa)    
Predicted Functional Partners:
DDB_G0289141
Poly [ADP-ribose] polymerase.
    
 
 0.823
adprt4
Poly [ADP-ribose] polymerase.
    
 
 0.823
adprt3
Poly [ADP-ribose] polymerase.
    
 
 0.818
DDB0191760
Uncharacterized protein.
    
 
 0.597
DDB0191728
Uncharacterized protein.
    
 
 0.597
DDB_G0287407
TPR repeat-containing protein DDB_G0287407.
    
 
 0.597
slmo
Protein slowmo homolog; Belongs to the slowmo family.
   
  
 0.462
crtA
Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity).
      
 0.450
ranA
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).
   
  
 0.411
ypel
Protein yippee-like; Belongs to the yippee family.
      
 0.410
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
Server load: low (22%) [HD]