STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lkhALeucine aminopeptidase; Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro). (606 aa)    
Predicted Functional Partners:
IptB
C2H2-type domain-containing protein.
 
      0.876
allC
Allantoicase; Utilization of purines as secondary nitrogen sources, when primary sources are limiting.
      
 0.869
taf2
Transcription initiation factor TFIID subunit.
      
 0.593
gghB
Gamma-glutamyl hydrolase B; Belongs to the peptidase C26 family.
     
  0.562
lpd
Dihydrolipoyl dehydrogenase, mitochondrial; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.544
psaA
Aminopeptidase.
  
 
0.532
idhM
Isocitrate dehydrogenase [NADP], mitochondrial; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
    
 0.511
DDB0205702
M20_dimer domain-containing protein.
  
 
 0.496
argE
Acetylornithine deacetylase.
  
 
 0.492
gsr
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.
   
 0.491
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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