STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rtoAProtein rtoA; May have dual functions, one in vegetative cells at starvation involving cell-type choice and a later function involving progression to the tipped mound stage. Involved in vesicle fusion in endo- and exocytosis. Involved in L.pneumophila intracellular growth. (367 aa)    
Predicted Functional Partners:
DDB0188089
SANT domain-containing protein.
   
 
 0.817
abcG18
ABC transporter G family member 18; Required for endocytosis and endosomal pH regulation.
    
 
 0.708
abcG2
ABC transporter G family member 2; Required for endocytosis and endosomal pH regulation. Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
    
 
 0.704
dstC
Signal transducer and activator of transcription C; Transcription factor that regulates gene expression during development. May play a role in regulating gene expression in response to osmotic stress.
      
 0.702
sigG
SrfA-induced gene G protein.
      
 0.701
DDB0218006
CYCLIN domain-containing protein; Belongs to the cyclin family.
      
 0.701
DDB0187595
Enhancer of polycomb-like protein.
    
 
 0.657
DDB0204231
Uncharacterized protein.
    
 
 0.653
tra1
Probable transcription-associated protein 1; Belongs to the PI3/PI4-kinase family. TRA1 subfamily.
   
 
 0.649
gtf2f1
General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity).
   
 
 0.639
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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