STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyp514A2Probable cytochrome P450 514A2; Belongs to the cytochrome P450 family. (500 aa)    
Predicted Functional Partners:
DDB0203555
PKS_AT domain-containing protein.
  
 0.579
DDB0218601
PKS_AT domain-containing protein.
  
 0.577
DDB0203528
PKS_AT domain-containing protein.
  
 0.577
cyp525A1
Probable cytochrome P450 525A1; Belongs to the cytochrome P450 family.
  
 
 0.567
ndufab1
Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis. May be involved in the synthesis of very-long-chain fatty acids. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity).
  
 0.514
cas1
Cycloartenol synthase; Converts oxidosqualene to cycloartenol (in vitro); Belongs to the terpene cyclase/mutase family.
  
 0.449
DDB0189319
2Fe-2S ferredoxin-type domain-containing protein.
  
 0.443
cyp51
Probable lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity).
  
   
 0.438
DDB0187496
PKS_AT domain-containing protein.
  
 0.422
DDB0188746
Carrier domain-containing protein.
  
 0.415
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.