STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mcfZMitochondrial substrate carrier family protein Z; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (301 aa)    
Predicted Functional Partners:
cprD
Cysteine proteinase 4.
    
   0.993
ancA
Mitochondrial substrate carrier family protein ancA; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.
   
 
 0.849
mcfM
Mitochondrial substrate carrier family protein M; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Transports folate across the inner membranes of mitochondria (By similarity).
  
   
 0.826
pole2
DNA polymerase epsilon subunit 2; Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity).
   
   0.793
drg1
Developmentally-regulated GTP-binding protein 1 homolog; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
    
   0.786
DDB_G0280783
UPF0235 protein; Belongs to the UPF0235 family.
    
   0.786
masB
Malate synthase.
   
  
 0.688
DDB0230179
Isocitrate lyase.
   
  
 0.688
DDB_G0287281
Citrate synthase-related protein DDB_G0287281; Belongs to the citrate synthase family.
   
 
 0.666
cs
Citrate synthase, mitochondrial; Belongs to the citrate synthase family.
   
 
 0.663
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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