STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0191851Uncharacterized protein. (691 aa)    
Predicted Functional Partners:
DDB0191073
RRM domain-containing protein.
   
 
0.850
sf3a2
Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex.
   
 
 0.656
DDB0219831
FHA domain-containing protein.
   
 
 0.537
Sf3b1
TOG domain-containing protein.
   
 
 0.532
prpf4B
Serine/threonine-protein kinase prpf4B; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
   
  
 0.498
cdc5l
Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. May also play a role in the response to DNA damage (DDR).
   
  
 0.477
U2af2
Uncharacterized protein.
   
 
0.450
Sf3a3
Zn finger-containing protein.
   
 
 0.436
DDB0190676
Uncharacterized protein.
   
    0.436
DDB0190921
Uncharacterized protein.
   
    0.425
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.