STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0219712Uncharacterized protein. (193 aa)    
Predicted Functional Partners:
lrlA
Latrophilin receptor-like protein A.
    
 
 0.993
pppB
Serine/threonine-protein phosphatase PP1; Protein phosphatase activity in vitro.
   
 
 0.818
dhcA
Dynein heavy chain, cytoplasmic; Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP; Belongs to the dynein heavy chain family.
   
 
 0.677
DDB0190820
Uncharacterized protein.
   
 
 0.659
rsmL
Rab GTPase.
    
 
 0.605
DDB0186876
Uncharacterized protein.
    
 
 0.440
dlcB
Dynein light chain, cytoplasmic; Acts as a non-catalytic accessory component of a dynein complex; Belongs to the dynein light chain family.
   
 
 0.415
dicA
Cytoplasmic dynein 1 intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chain mediates the binding of dynein to dynactin.
   
 
 0.408
PLK
Probable serine/threonine-protein kinase PLK; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
   
 
 0.402
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.