STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IptBC2H2-type domain-containing protein. (522 aa)    
Predicted Functional Partners:
IptC-1
Uncharacterized protein; Belongs to the IPP transferase family.
  
  
0.939
cdk5rap1
CDK5RAP1-like protein; Probable regulator of CDK5 activity; Belongs to the methylthiotransferase family. MiaB subfamily.
  
  
 0.895
lkhA
Leucine aminopeptidase; Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
 
      0.876
iptA
Adenylate dimethylallyltransferase; Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin phytohormones like isopentenyl adenine or discadenine which controle spore formation and viability.
      
 0.792
purD
Phosphoribosylformylglycinamidine cyclo-ligase; In the N-terminal section; belongs to the GARS family.
     
 0.740
fsjA
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
  
  
 0.654
DDB0169374
Uncharacterized protein.
  
  
 0.586
fsjC
pre-rRNA 2'-O-ribose RNA methyltransferase; RNA 2'-O-methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
  
  
 0.581
grpE
GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
   
  
 0.524
efa1G
Glutathione S-transferase domain-containing protein.
     
 0.505
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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