DDB_G0291608 protein (Dictyostelium discoideum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DDB_G0291608

Putative uncharacterized protein DDB_G0291608. (919 aa)

Predicted Functional Partners:

DDB0205163

0.535

ubc9

0.533

pcna

0.532

SUMO

0.532

DDB_G0287153

0.530

DDB0188371

0.437

top1

0.405

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB0188371	DDB0205163	Q54HN3	Q54SX2	SP-RING-type domain-containing protein.	Uncharacterized protein.	0.619
DDB0188371	DDB_G0287153	Q54HN3	Q54KR7	SP-RING-type domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.749
DDB0188371	DDB_G0291608	Q54HN3	Q54EQ9	SP-RING-type domain-containing protein.	Putative uncharacterized protein DDB_G0291608.	0.437
DDB0188371	SUMO	Q54HN3	Q8N0B4	SP-RING-type domain-containing protein.	Small ubiquitin-like protein.	0.765
DDB0188371	top1	Q54HN3	Q54RC3	SP-RING-type domain-containing protein.	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. TThe free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus rem [...]	0.501
DDB0188371	ubc9	Q54HN3	Q9NGP4	SP-RING-type domain-containing protein.	Sumo-conjugating enzyme ubc9; Accepts the ubiquitin-like protein sumo from the E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase.	0.843
DDB0205163	DDB0188371	Q54SX2	Q54HN3	Uncharacterized protein.	SP-RING-type domain-containing protein.	0.619
DDB0205163	DDB_G0287153	Q54SX2	Q54KR7	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.830
DDB0205163	DDB_G0291608	Q54SX2	Q54EQ9	Uncharacterized protein.	Putative uncharacterized protein DDB_G0291608.	0.535
DDB0205163	SUMO	Q54SX2	Q8N0B4	Uncharacterized protein.	Small ubiquitin-like protein.	0.400
DDB0205163	pcna	Q54SX2	Q54K47	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.	0.880
DDB0205163	top1	Q54SX2	Q54RC3	Uncharacterized protein.	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. TThe free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus rem [...]	0.484
DDB0205163	ubc9	Q54SX2	Q9NGP4	Uncharacterized protein.	Sumo-conjugating enzyme ubc9; Accepts the ubiquitin-like protein sumo from the E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase.	0.982
DDB_G0287153	DDB0188371	Q54KR7	Q54HN3	UBIQUITIN_CONJUGAT_2 domain-containing protein.	SP-RING-type domain-containing protein.	0.749
DDB_G0287153	DDB0205163	Q54KR7	Q54SX2	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.830
DDB_G0287153	DDB_G0291608	Q54KR7	Q54EQ9	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Putative uncharacterized protein DDB_G0291608.	0.530
DDB_G0287153	SUMO	Q54KR7	Q8N0B4	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Small ubiquitin-like protein.	0.982
DDB_G0287153	pcna	Q54KR7	Q54K47	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.	0.837
DDB_G0287153	top1	Q54KR7	Q54RC3	UBIQUITIN_CONJUGAT_2 domain-containing protein.	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 5'-OH DNA strand. TThe free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus rem [...]	0.427
DDB_G0287153	ubc9	Q54KR7	Q9NGP4	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Sumo-conjugating enzyme ubc9; Accepts the ubiquitin-like protein sumo from the E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase.	0.902