STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mgp1Mental retardation GTPase activating protein homolog 1; Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying. (920 aa)    
Predicted Functional Partners:
gtaK
GATA zinc finger domain-containing protein 11; Transcription factor that regulates morphogenetic cell movement during development.
      
 0.883
rac1C
Rho-related protein rac1C; Overexpression promotes the formation of filopodia and membrane ruffles.
   
 
 0.783
racA
Rho-related protein racA.
   
 
 0.783
racF1
Rho-related protein racF1; Might act in concert and/or share functions with other members of the RHO family in the regulation of a subset of cytoskeletal rearrangements that are required for these processes.
    
 
 0.781
rac1A
Rho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family.
    
 
 0.781
rac1B
Rho-related protein rac1B; Overexpression promotes the formation of filopodia and membrane ruffles.
    
 
 0.781
racB
Rho-related protein racB; Belongs to the small GTPase superfamily. Rho family.
    
 
 0.781
racC
Rho-related protein racC; Belongs to the small GTPase superfamily. Rho family.
    
 
 0.781
racD
Rho-related protein racD; Belongs to the small GTPase superfamily. Rho family.
    
 
 0.781
racQ
Rho GTPase.
    
 
 0.781
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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