STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Syn1At-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (333 aa)    
Predicted Functional Partners:
sybB
Synaptobrevin-B; Involved in the targeting and/or fusion of transport vesicles to their target membrane; Belongs to the synaptobrevin family.
   
 0.969
sybA
Synaptobrevin-A; Involved in the targeting and/or fusion of transport vesicles to their target membrane.
    
 0.969
sec1
Protein transport protein sec1; Involved in the vesicle trafficking. Binds syntaxins (By similarity); Belongs to the STXBP/unc-18/SEC1 family.
  
 0.939
snpA
Alpha-soluble NSF attachment protein; May be required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity). Involved in vesicle fusion with nsfA and probably SNARE proteins; Belongs to the SNAP family.
   
 0.925
DDB0188794
Uncharacterized protein.
    
 0.915
Syn1B
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
  
 
 
0.904
nsfA
Vesicle-fusing ATPase; Required for vesicle-mediated transport. Involved in endocytosis and endosome-endosome fusion. May be required for transport from the endoplasmic reticulum to the Golgi stack, and for the fusion of transport vesicles within the Golgi cisternae. Required for cell polarity, locomotion and chemotaxis.
   
 0.899
cprD
Cysteine proteinase 4.
   
   0.839
DDB_G0269942
Uncharacterized protein; Belongs to the synaptobrevin family.
   
 0.838
syn5
t-SNARE family protein.
    
 0.768
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.