STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bcs1laProbable mitochondrial chaperone BCS1-A; Chaperone necessary for the assembly of mitochondrial respiratory chain complex III; Belongs to the AAA ATPase family. BCS1 subfamily. (421 aa)    
Predicted Functional Partners:
mrpl16
60S ribosomal protein L16, mitochondrial.
   
 
 0.608
mrpl17
Probable 39S ribosomal protein L17, mitochondrial.
   
 
 0.604
mrpl27
Probable 39S ribosomal protein L27, mitochondrial.
  
 
 0.598
DDB0191671
Uncharacterized protein.
  
 
 0.596
rps14
40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.
   
 
 0.582
rps5
40S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.
   
   0.576
psmG1
Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2; Belongs to the PSMG1 family.
   
   0.576
hprT
Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
  
  
 0.572
rps15a
40S ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family.
   
 
 0.566
mrpl21
Probable 39S ribosomal protein L21, mitochondrial.
  
 
 0.548
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.