STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
valS2Probable valine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1051 aa)    
Predicted Functional Partners:
efa1G
Glutathione S-transferase domain-containing protein.
 
 
 
 0.917
valS1
Probable valine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 
0.905
mcysS
Probable cysteine--tRNA ligase, mitochondrial.
  
  
 0.903
thrS1
Probable threonine--tRNA ligase 1, cytoplasmic; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.899
thrS2
Probable threonine--tRNA ligase 2, cytoplasmic; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.898
cysS
Cysteine--tRNA ligase, cytoplasmic.
  
  
 0.895
gluS
Probable glutamate--tRNA ligase, cytoplasmic; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
  
 
 0.878
wars2
Tryptophan--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.877
bxdc1
Ribosome production factor 2 homolog.
 
 
  
 0.865
leuS
Leucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
0.864
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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