STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB_G0288237UDENN domain-containing protein. (1488 aa)    
Predicted Functional Partners:
DDB0216684
UDENN domain-containing protein.
     
 
0.800
DDB_G0294569
Rab GTPase.
    
 
 0.502
DDB0204889
Uncharacterized protein.
    
 
 0.502
DDB_G0294583
Ras GTPase.
    
 
 0.502
DDB0206402
Rab proteins geranylgeranyltransferase component; Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins; Belongs to the Rab GDI family.
   
 
  0.416
rab7A
Ras-related protein Rab-7A; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Involved in lipophagy, a cytosolic lipase-independent autophagic pathway (By similarity); Belongs to the small GTPase superfamily. Rab family.
     
 0.413
rabK2
Ras-related protein RabK2.
     
 0.413
DDB_G0294571
Rab GTPase.
     
 0.413
rabK3
Ras-related protein RabK3; Belongs to the small GTPase superfamily. Rab family.
     
 0.413
rabN2
Ras-related protein RabN2; Belongs to the small GTPase superfamily. Rab family.
     
 0.413
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.