STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
halProbable histidine ammonia-lyase. (539 aa)    
Predicted Functional Partners:
uroc1
Probable urocanate hydratase.
 
  
  0.948
amdhd1
Probable imidazolonepropionase.
 
 
 0.947
DDB_G0273787
Hal-like protein DDB_G0273787/DDB_G0273081; Belongs to the PAL/histidase family.
  
  
 
0.912
argC
N-acetyl-gamma-glutamyl-phosphate reductase; In the C-terminal section; belongs to the NAGSA dehydrogenase family.
   
  
 0.832
DDB0188301
Uncharacterized protein; Belongs to the arginase family.
  
 
 0.782
ftcd
Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
  
  
 0.595
prodh
Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate.
      
 0.574
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
 
 0.546
DDB0186514
Amidohydro-rel domain-containing protein.
  
 
 0.538
argD
Probable acetylornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
  
 0.529
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.