STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cutcCopper homeostasis protein cutC homolog; Involved in copper homeostasis. (280 aa)    
Predicted Functional Partners:
ccs
Probable copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutases. In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.
     
 0.585
DDB0169374
Uncharacterized protein.
   
  
 0.585
atox1
Copper transport protein ATOX1 homolog; Could bind and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity).
      
 0.575
arsB
Putative transporter arsB.
   
  
 0.528
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
  
    0.508
DDB0205318
RNA_helicase domain-containing protein.
   
  
 0.495
tpiA
Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.
      
 0.491
DDB0186554
ZT_dimer domain-containing protein.
  
  
 0.469
guf1
Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
     
 0.454
DDB0169521
Tr-type G domain-containing protein.
     
 0.454
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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