STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0187266Uncharacterized protein. (388 aa)    
Predicted Functional Partners:
DDB0217507
Uncharacterized protein.
   
 
 0.997
wrn
ATP-dependent DNA helicase RecQ family protein.
   
 
 0.942
DDB0190238
Uncharacterized protein.
  
 
 
0.914
Rfa1
Uncharacterized protein.
    
 
 0.891
DDB0187005
Uncharacterized protein.
    
 
 0.759
Xrcc3
RECA_2 domain-containing protein.
    
 
 0.735
ku70
ATP-dependent DNA helicase ku70; Involved in non-homologous end joining (NHEJ) DNA double strand break repair.
    
 
 0.709
rad51c
DNA repair protein RAD51 homolog 3; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily.
    
 
 0.691
ku80
X-ray repair cross-complementing protein 5; Involved in non-homologous end joining (NHEJ) DNA double strand break repair.
   
 
 0.680
atr1
Probable serine/threonine-protein kinase atr1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q (By similarity); Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 
 0.672
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.