STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pex5Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. (641 aa)    
Predicted Functional Partners:
DDB_G0284681
Uncharacterized protein.
   
 
 0.998
pex7
Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import. Belongs to the WD repeat peroxin-7 family.
    
 0.998
pex13
Probable peroxisomal membrane protein PEX13; May be a component of the peroxisomal translocation machinery; Belongs to the peroxin-13 family.
   
 0.994
pex12
Putative peroxisome assembly protein 12; Required for protein import into peroxisomes; Belongs to the pex2/pex10/pex12 family.
   
 0.988
pex10
Peroxisome biogenesis factor 10; Involved in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family.
   
 0.985
pex6
Peroxisomal biogenesis factor 6; Required for biogenesis of peroxisomes; Belongs to the AAA ATPase family.
   
 
 0.967
hacl1
Probable 2-hydroxyacyl-CoA lyase 1; Catalyzes a carbon-carbon cleavage reaction; cleaves a 2- hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde; Belongs to the TPP enzyme family.
 
  
 0.942
pex11
Peroxisomal membrane protein 11 homolog; Involved in peroxisomal proliferation. Could participate in peroxisomal elongation or fission. May be involved in parceling of peroxisomes into regular quanta (By similarity); Belongs to the peroxin-11 family.
   
 
 0.941
pex19
Putative peroxisomal biogenesis factor 19.
    
 
 0.932
pex16
Peroxisome biogenesis factor 16; Required for peroxisome membrane biogenesis; Belongs to the peroxin-16 family.
      
 0.929
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.