STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dlpBDynamin-like protein B; Involved in cytokinesis. May hydrolyze GTP. (808 aa)    
Predicted Functional Partners:
gxcB
Rac guanine nucleotide exchange factor B; Involved in the regulation of the late steps of the endocytic pathway.
   
 
 0.831
GxcKK
Uncharacterized protein.
    
 
 0.830
DDB0187425
G domain-containing protein.
   
 
 0.830
dymA
Dynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway.
      
 0.791
dymB
Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
      
 0.787
dynB
Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis.
    
 
 0.781
DDB0204578
GB1/RHD3-type G domain-containing protein.
   
  
 0.760
DDB_0206311
Protein SEY1 homolog; Probable GTP-binding protein that may be involved in cell development; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily.
   
  
 0.704
dynA
Dynactin 150 kDa subunit.
   
  
 0.632
DDB0218220
TPR_REGION domain-containing protein.
    
 
 0.528
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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