STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GxcPUncharacterized protein. (971 aa)    
Predicted Functional Partners:
DDB_G0295817
Uncharacterized protein.
   
 
 0.905
DDB0184513
Uncharacterized protein.
   
 
 0.905
kif12
Kinesin-related protein 12; Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). Required for cytokinesis. May be involved in a vesicle-mediated transport of myosin II, the Aurora kinase (aurK) and other proteins along mitotic extracellular microtubules toward the center of the cell and the cleavage furrow in order to ensure cell division coupled to mitosis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.815
mps1
Probable serine/threonine-protein kinase mps1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
  
 0.714
kif13
Kinesin-related protein 13; Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). Cooperates with dynein to control the spindle elongation rate, but is dispensable for mitosis. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily.
   
  
 0.653
aurK
Aurora kinase; Part of a chromosomal passenger complex. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
   
 
 0.592
DDB0205843
Uncharacterized protein.
   
  
 0.578
rfc4
Probable replication factor C subunit 4; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template (By similarity).
   
 
 0.575
GxcQ
DH domain-containing protein.
     
0.573
DDB0205569
Uncharacterized protein.
   
  
 0.572
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.